إِنَّ أَخَاكَ قَادِمٌ
Indeed, your brother is coming.
إِنَّ: an emphatic particle that assigns the accusative case to its noun.
أَخَاكَ: the accusative noun of inna, marked by alif; kāf is the possessive suffix.
قَادِمٌ: the nominative predicate of inna.
The shift from “أَخُوكَ” to “أَخَاكَ” is a grammatical consequence of adding inna. The information itself remains unchanged; what changes is the speaker's rhetorical reinforcement.