أَأَنْتَ فَعَلْتَ هَذَا؟
Was it you who did this?
Where the action is presupposed, the focus is on identifying its agent, highlighted by anta.
أَرَاغِبٌ أَنْتَ عَنِ الْأَمْرِ؟
Are you averse to the matter?
Here it is the quality or predicate that is in focus.
أَيَوْمَ الْخَمِيسِ قَدِمْتَ؟
Was it on Thursday that you arrived?
This focuses on the time expression, an adverbial element. Placing a particular element immediately after the interrogative helps identify the precise part under investigation.