مَا شَأْنُكَ وَعَمْرًا؟
Translation: What is your concern with Amr?
مَا: interrogative topic in nominative position.
شَأْنُكَ: nominative predicate; shaʾnu is a first term of iḍāfa and -ka the genitive possessive pronoun.
وَ: wāw of accompaniment.
عَمْرًا: accusative accompaniment complement.
Shaʾn is a noun, not a verb. The “verb in meaning” refers to the sense conveyed by the whole construction.