لَا طَاعَةَ لِمَخْلُوقٍ does not authorize opposing every instruction. Respectful cooperation within lawful duties is essential to family, study, and society. The dividing line is lawful conduct versus disobedience to Allah.
If parents reasonably ask for help, personal inconvenience alone is not a reason to cite this report as justification for refusal. Similarly, a demanding but legitimate assignment or institution rule is not automatically a violation of religious conscience.
مَعْصِيَةِ الْخَالِقِ means “disobedience to the Creator.” These words specify the prohibited setting; they do not invalidate all human direction.